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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25823a450e5c3c8d1a2f15b44e3592139a2a59baf481bb1a9a508a511d9026d8' 
  AND token = '+b9AeBkjyVfr7RpkYDGw1KWK7/bR63lwnfjfP8kKoHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}