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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f62179d63c12e91014134c7d9c72f8bdf49634ee53ffbc6889c6264116e0d7ea' 
  AND token = 'tTuBlc65gZLIk2EFsNu6XFcqm+4ZU2tmmlq1TB4RWHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}