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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d4f6771789982b4dc71bf3a08cb1bba5e7faaae6910205c6222ab857b02a9db' 
  AND token = 'PsI5D1yoah0ScrayBwx1OVNr0HI/H7msHXpmUR1Q1tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}