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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '588cb6fcfa6ff5b7e72a62cad34a157016bd90a8f9080b57aa2df60c10bab3b1' 
  AND token = 'nOO+kbDKPk0XXoyS/qisLM4JKcwH/rRe0P6sXLbw35U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}