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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cf61b16db5d3403b4d1db713c2dc45ea504db3b79ff107480c373236bf2004b' 
  AND token = 'W10zthx/GlDgmAyqvxTm0qSEal+Rc6LkywN9KL80uLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}