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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73af4be6313a2fe8dfd32b7e801adb1310f75deeb2cc4ca01a804f9dacbb0099' 
  AND token = 'vzzK4/3VZHT6yMJT+PEaG1q/l552BaAEXy5xgfvrHlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}