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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1544513a7d30712703b7ebef8e1949c6c46aa516b3eed26b5a601a6f7aba12c1' 
  AND token = 'RRm74IeA9DmqH4uYW5XL310ArcFeZ5rLHDJTj8WFmj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}