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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5a08531f036b6094883e291c58552c6bb819d64b75ae58e65bfbb3f55569cc7' 
  AND token = 'HSpVeARCD5WtuMf+rVIyxr83FEL6GSdBXaOUmaYbYXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}