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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c436b330e0502787a6c345571bd2d3656fdc6dcc432c47b489b8590a4e0533f' 
  AND token = 'HowTmeqY6JCXvT9ClrXkk5y5T268rKZiGtiijUk8PtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}