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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8b57e49289f45342733f9a6ffd06daa861dfe1e11a5061a0ef9e2485e960604' 
  AND token = 'GgwbZnvJxRNppSf4AAybf/sBDRFtf5mtjo/cGnLemu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}