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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54f78a66f52ebcd9a6e0ae13d87a9fae3a823b0a104766b8826f1c6eae7ec266' 
  AND token = 'IB6QrdQUr7egVHxYwLC2SytTexF1kagact7RkfmHzMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}