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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '548d6e2313791ae5ff6476f14012ef3c3b8658367740a4bf9b5f671c2ad97c82' 
  AND token = 'aSAmip6RpQIhhmGzh7ORl2hJn5Z5F3QTSgchF1zrEaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}