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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1b416ef8c1d1376f0e67323497866659e2a48c2dc05758045e22aa0a48ddacb' 
  AND token = 'REkW9Vm3O7EMMo7/Ua3cmXvBX25QIqhtvn2CdF/UVxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}