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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50b1e05569a3e82a772370d3aee76e04553c0256f9ab4b5f698c74d97fe7b923' 
  AND token = 'Mcfwam44HkwkNkGzXsP34O2+m7DO+53ZI8iPmZ6R2Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}