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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aa21823d993178560166db3db480e6fd8f2e832f0130d2e6e1e6ecaa6f17319' 
  AND token = 'Upu2XmNNxGgvtwcWBYTpPXQMaOboJnBfO+raQXyc9JY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}