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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e643001b5a9c20ec99475488cc74e6b751fe58d22ee55c38c096a94916de187' 
  AND token = 'l/yfx/2yquDEcKejmMCnJleNZTty3wqKw0rGS6xh22U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}