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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee4897b249a32a59a73360091480775a44b334bae4011f9d8efa4b6d5290d9d5' 
  AND token = 'MmuUuP2PFxzxbXxlthxVOsUfv/433AZtSVB/6CjH9es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}