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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e23525da76ad449a69dea2207d90d3945e64a1139063418db91584ceda8bebd4' 
  AND token = '1TruVmUQN2mj84fySDgolDYe0wpo1yi9FrzHb46zbto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}