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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '390ffa1e8a1ffbf805b0c75fc469717ab5114c849dcd3bf7b4ddee40c2029db5' 
  AND token = 'VX88pttxbb/DJ5flT4WMcAsbcabYi1aBn92YFsWAs/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}