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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd705401b5af93fcd5ef73e9a134fc27a1c65e261f09e81ee3a322d69608724ed' 
  AND token = 'zM1TXq9cdut0k/5i/Nt6jxvWraSIBRQhD8PB6sBiT00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}