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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48bb659765cc8ec46b3fcc061007c2d1b5bb1c5fcbf8bf67fb67d6599c676b20' 
  AND token = 'icKhdD5qQpYQmnzSUVfm7oGP35igKndbzhqNzqLtFWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}