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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec05052d6541d02f12bd1347bb17c4c3d1ab20adae3c438b0c354ea46e0eee58' 
  AND token = 'uJofDl5Qj0XcMkiTcL5rLW5WpjSJvOfgVr49mE9mCTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}