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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a84ae7b2e69d53dc28f80f595f55f158e08cde43ee64c88794dc1f06e615553' 
  AND token = 'qR0PjyDJgJZE0hySlmV6z6/4X2aRMOXfDbWVh6hgJGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}