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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fd7cd732053f4d789426f652a80cd22e79c0e31ff76616b2b967cfea551c4ad' 
  AND token = 'XE4aLNdSnqe4//wycGmYbWFaxPSzi7C80TFBvgBTcNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}