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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f4b0fe95eba27c2658b583a6e301def030ac0e9d6b4637d7ea0b81c4ec24f02' 
  AND token = 'ji3qf5DKQXNd5K9m8rfqRkICxGeo3Q7iQdgq8C6Q39U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}