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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d596d98e5c504e7d77a27c511e899ec18add4905fb69f11399d4c5df3b59389' 
  AND token = 'BQXD/Do5MhY7u593F61HSKpx2D6c4t8ZmbIgS7X3g58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}