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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd28525c49b6fd65bd43e83e6a78be58a009dd2cf7e7c42a303f73649e5b6c813' 
  AND token = 'AI7e1+mPiFYDYqkOzOtvyY7h3LmooORQUozCxAOLZcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}