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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '078dd193473370f4ca64309e9b446da1624ee67ad253673600b99c47cc4f41d4' 
  AND token = 'SV0vQjIXFwFTQ2Z2QR/uZT9nYbr6jEpFSeD6Zquk4LY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}