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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fd1c25164790b311f5ffa80cbce6e3f06af4e4dd02ce7e864a04dfb98b0e194' 
  AND token = 'tZZGC0gRuetMG/AJDYkYLO5UXtTlyRbfrA8ltMAKOVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}