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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d51d36d6a2cae3c097026514a38fb2250987d4ff0011edf04169b7005d478b1' 
  AND token = 'NfGTfpE6YJAin+OHR6/Yzb8eVLibkzieOAuHWXy1tnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}