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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67d64f6ce9188ce616a94a110178778ba8d4be542e450419ce7e266a36f3b884' 
  AND token = 'z/pCBJhi2MWJ7sK6F1z95t7ihTValbEERyFC1+DzEZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}