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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c77ccd24c3ec6d9459c85752fb7f36e231b05318745a1175a3e2d1cca3defc50' 
  AND token = '0OiTwNNvAuJg1jOBKnVaz1kpP5EWJTXCJbl0+12bHSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}