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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01d4e9fee963a16f4ae37f805d1e3594114f66a22657a6cf7bb55dfd38c0b898' 
  AND token = '6vIH2bFMFN7zfFwYeHlce/r+nLIrQh5OY3FR5kn8kTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}