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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bc02c7be2e81cee8d42610b9d9ceb043bf8effcf158557289b36480146b1f57' 
  AND token = 'DiQgdxb0aA/Xh8z5W9X/DnqEcabGaaskZDtPOarWT5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}