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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8cbdc5225629ae54f2ea03604e4876bb2bc5be85c4939d7f5d7491059f079c' 
  AND token = '4jFJF0cG9nKL56KZ3V9p4rpi6DPEbBOCFnuIQ7/QY/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}