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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34ddbb0014bd0b0efa08957f42c0499105ead958cdb4d1588e3b88f422ed8c3c' 
  AND token = '/VY6aHh+D1CWxfcEViKb2dnWzUs4v1l3vxn10T7H+rU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}