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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54a290cd60bb084d435a66a782d2c0fa4a29854452e9dd6b4cad08266b5a1602' 
  AND token = 'jmCgEIJE5PBXsNYpJPLFHIa4pxqenH2/e20+3Qb7ff0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}