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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f583b1a7d08e1a7e2cdd645086ce121fd83315fa062fef6dee9dc324942c7d69' 
  AND token = 'GValep/9oc3EZ5vhXVA0E9WS+GV06IFSnNnKSkdWM9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}