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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17f66200b0ab592dca81f8ff378e03042ebb112a2ead850ee92da7a3228669e5' 
  AND token = 'uO9WSdty9mxm/a8amBFL3wYBVps0u/v09nCmV+4Wrlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}