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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a7d825ad73e55aad95d71f34cace55481d186dffd3935c3904ba44d4c963f54' 
  AND token = 'PJ4mh+wXr+TtfkeN2jWzPxzGlYSPz5B2s/34Jtfvp5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}