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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b5d9ed481fad89fbeb375e72ddfd91844495114a8c95ed59690f79019e4071' 
  AND token = 'EilO6adQ0SYIFpKVuW188+ySi/2yCpvRKwISIft0nVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}