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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b59c1a3dfd29e4f56126bcd3c237e2a2f42a0fa09dff976a2f6a66289966d3ef' 
  AND token = 'oC/dv9TkUgw3tDvdBLH1Qgkv49GCzJqI1f1atDzlybE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}