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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e4bc29a6b0de2e856de9a532142984e4b039d310685de663eaa02ed935d7f1f' 
  AND token = 'ij7v9DP1lj68/f7PEoZQnHxxOP9hGEkpBWwCo7Ju33Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}