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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72cf5d098f4c96a32dd7a0371d6c4b9b0d45567179b58b20522e98f53f36c6a9' 
  AND token = '8F2Qdq38xsscNT9GBkQYxA+VrwaKfi08OClG7s/4ah4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}