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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4875f86d400ddf0538b5b51b316c1b1e5e6ea7d3e69e0096426bcea8d42fc1b' 
  AND token = '0O3M1JUVQIgVGUWNHEnOVUxSFgwIuPWVkkCgbPh8l84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}