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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e1fb7a7c50520372b9d20e6aea302b82e63921511cbb8d5b8109c145fa50480' 
  AND token = 'P3d60E5fri8p5OdYxHcyhPMzDBeSXfIu4KZbjHEa2g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}