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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec2810ace55ab1090ae9c95b5ef70a634ac519cb4808a0e924e1e95e55c43931' 
  AND token = '3c223/3eEL/YsEPb4lqJEAYgGb0FNM+2QPg8sszcLc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}