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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ead8fe7e3fc67048a533247cb2d5c0ff6ae1fcba0d42fdf1c986c94608310ffb' 
  AND token = 'JVFFQT7LHCy/tBczfS58yylC09UfOMyXfQg2kUpmMwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}