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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0318806c339f3eaf59b1010d38c06ec85ec2c7075f399a06656d69a92a4b763a' 
  AND token = 'NjjH4xPHdxjsGzEGUCr9QA1JE867JMMjA+iTY5MBuKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}