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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3f1f3ca22fe3f98458e36a71a1c28257b37792c5537c9af2dedf7ce3bc74f80' 
  AND token = 'M7qYf57NuH6hc1kEqr19cOIhZ0kRrgQAlDmnXdUzxTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}